The word “sulfur,” in my mind, is inexorably linked back to Mr. Burcik’s high school chemistry class, when we were given soft, pungent, yellow chunks to mix with other chemicals.  When elemental sulfur is exposed to air, it forms sulfur dioxide, which burns the inside of the nose and stinks up the whole chemistry wing of the building.

Sulfur isn’t just about the pungent sting of a burnt match, though, and in wine it’s not just about the presence of sulfites.  Sulfur-based aroma compounds are found at all stages of the winemaking process, and can range from downright noxious to fruity and pleasant.  Let’s take a look at some of the various sulfur-containing aroma compounds found in wine.

Elemental sulfur is sprayed in vineyards to control growth of microorganisms on grapes.


Perhaps when we hear of “sulfur” in wine, we think first of sulfites.    The term “sulfites” refers to the various forms of sulfur dioxide present in wine. The original application of sulfites was burning sulfur candles in amphorae (the clay vessels used to make wine in ancient times).  Ancient winemakers (be they Greeks, Armenians, Egyptians, or Romans, depending on whom you ask) probably didn’t know why burned sulfur (sulfur dioxide, or SO2) helped preserve their wine, but the use of sulfites has been fairly ubiquitous in winemaking since and continues to this day.

Sulfites are used for many reasons in winemaking to (1) inhibit growth of wild yeasts and bacteria, (2) bind with acetaldehyde and other oxidizing molecules, preserving color and aroma, and (3) inhibit some polyphenol oxidases in grape juice, reducing browning.

The aroma characteristics of sulfites are unmistakeable and can be obvious when a winemaker has been heavy-handed. The best descriptor I can think of is struck match, but there is more to smelling sulfites than aroma. Sulfites create a trigeminal response, meaning they irritate the nasal passages, creating a stinging sensation.

Sulfides and Mercaptans

If sulfites are regarded as oxidized sulfur, then sulfides and mercaptans are at the other end of the oxidation spectrum: reduced sulfur. These compounds have a real stink to them.

Hydrogen Sulfide

If you’ve ever made wine, been around winemaking, or even opened a stinky bottle of wine (had a bad experience with a Languedoc recently… whoa!), you probably are familiar with the smell of hydrogen sulfide (H2S). It smells like rotten eggs, and it’s commonly found in wine.

This malodorous molecule can come from two sources during fermentation: (1) excessive elemental sulfur sprayed on grapes and (2) nutrient deficiency in yeast. The first case seems easy enough to understand (sulfur is reduced by yeast enzymes), but the origins of H2S due to yeast nutrient deficiency are slightly more subtle.

Yeast require a source of nitrogen to complete fermentations. Low nitrogen can lead to stuck, and as many home fermenters know, stinky fermentations. In the absence of nitrogen, which is a principal component of the protein building blocks, yeast will begin to degrade amino acids in order to make the specific amino acids they need. When sulfur-containing amino acids like cysteine and methionine get degraded, they release sulfur groups that are processed into various sulfur-containing compounds, hydrogen sulfide among them. To prevent this, winemakers often measure YAN (yeast available nitrogen), supplement fermentations with yeast nutrients, choose yeast strains carefully (if inoculated), and aerate the fermenting wine.

Hydrogen sulfide in wine can suppress perception of fruit aromas, even if it’s below the point where the wine smells like rotten eggs. Luckily for many wine drinkers, it is very volatile and blows off quickly. It has been speculated that decanting wine (or just aerating if all you’ve got is a pitcher) can aid in perception of fruit and other pleasant aromas by blowing off hydrogen sulfide.

Mercaptans and Disulfides

Another set of players in our sulfurous rogue’s gallery are the mercaptans. These sulfur compounds are also formed by the degradation of amino acids and smell rather like some cruciferous vegetables. Examples include methyl mercaptan (cabbage, garlic, burnt rubber) and ethyl mercaptan (the compound added to natural gas to warn us of gas leaks). The human nose is highly sensitive to these compounds (detected in the low parts-per-billion range). Winemakers can diminish the amount of mercaptans by copper fining, but this practice is risky given the legal limits on copper in wine in many countries. This could be one reason why the Romans drank from goblets of copper and lead, another heavy metal that binds mercaptans. Indeed, if you smell some of these aromas in a wine and can find a pre-1982 copper penny (modern pennies are mostly zinc), you could try a copper fining experiment for yourself by dropping the coin in your glass.

But as if mercaptans didn’t sound bad enough, these compounds can react (sometimes with each other) to form sulfides. Examples include dimethyl sulfide (canned corn, seafood, cooked cabbage) and methyl ethyl sulfide (onion), ethyl disulfide (rubber) and dimethyl trisulfide (fish, cabbage). Sulfides and disulfides cannot be fined with copper. In fact, there’s not much a winemaker can do to get rid of them. Luckily, sulfides and disulfides are perceived at a higher threshold than mercaptans and usually are not present in high enough amounts to be detectable in wine. However, disulfides can still be problematic while aging in the bottle. (see inset)

Aside: Screwcaps and Reduction

The composition of many sulfur compounds in wine depends on what is known as the reduction-oxidation (redox) potential in wine. During fermentation, wine is a chemically reducing environment, where mercaptans and thiols can thrive without fear of reacting with other thiol groups to form disulfides. After fermentation ends, the redox potential of a wine becomes more oxidizing (by aeration, racking, etc.). If mercaptans are around in high enough numbers, they can react to form disulfides. If they are below the detection threshold, these might go unnoticed by the winemaker and bottled with the wine.

What does this have to do with screwcaps? Closures, it turns out, have an awful lot to do with the redox state of a wine. Some closures allow lots of oxygen ingress (synthetic cork, bag in box, etc.) while some allow little oxygen (a good natural cork) and some barely any oxygen at all (screwcaps). It’s been speculated that the small amount of oxygen ingress can stabilize disulfides in bottle, preventing them from breaking apart into the more potent mercaptan aroma compounds. This could explain why a “reductive” fault or flaw is often attributed to screwcapped wines, and the screwcap is given the blame. Whether this is justified or not is up for debate, and some would argue that screwcaps help preserve volatile thiol aromas like passion fruit and grapefruit (think about New Zealand Sauvignon Blanc, religiously bottled under screwcap). There is still considerable debate on this topic as screwcaps become more widely adopted around the world.

Volatile Thiols

Volatile thiols are another set of sulfur compounds that affect wine aroma. In truth, thiols and mercaptans are the same type of molecule (both have -SH groups), but in most wine circles, the difference is lexicographical. Thiols smell good and mercaptans smell bad. It’s kind of like how “finish” is good but “aftertaste” is bad. Anyway, one notable volatile thiol 4-mercapto-4-methylpentan-2-one (4-MMP), a common descriptor of which ranges from “boxwood” to “cat pee”. It’s a major contributor to the varietal character of Sauvignon Blanc. Other thiols include 3-mercaptohexanol (grapefruit, passionfruit) and furfurylthiol (coffee, toasty oak, popcorn).

A very honest example of 4-MMP in Sauvignon Blanc

A refreshingly honest example of 4-MMP in Sauvignon Blanc

Most volatile thiols are produced by grapes themselves, but are present in grape juice in a kind of “masked” form. Many are found conjugated to the sulfur-containig amino acid cysteine (remember cysteine?). During fermentation, however, yeast enzymes separate the volatile thiols from cysteine, allowing their fruity aromas to be perceived. The French enologist Emile Peynaud described this mechanism as a way to taste some of the tropical flavors found in Sauvignon Blanc grapes: holding the juice in the mouth for a bit and allowing the natural enzymes in saliva to release the aroma compounds. Only recently (after his death) was he proven right.

Sulfur roundup

Many prominent aromas in wine are derived from sulfur-containing compounds. Some of them are off-putting (e.g., cabbage and rotten eggs), while some are pleasant and give wines their very varietal character. We have discussed some of the major groups of sulfur-containing aromas in wine and some ways winemakers can modify them to their advantage, either by copper fining, aerating, or by choice of closure.

Sulfur compound Smells like… Origin in wine
Sulfur dioxide (aka sulfites, SO2) struck match Produced naturally by yeast, added as a preservative/antioxidant/antimicrobial agent.
Hydrogen Sulfide (H2S) rotten eggs Nitrogen deficiency during fermentation leading to metabolism of sulfur-containing amino acids, reduction of residual sulfur
Mercaptans (Ethyl mercaptan, methyl mercaptan) burnt rubber, garlic, natural gas leak Nitrogen deficiency during fermentation leading to metabolism of sulfur-containing amino acids
Sulfides (Dimethyl Sulfide, Ethyl Methyl Disulfide, etc.) canned corn, garlic, cabbage, rubber Oxidation of mercaptans
Volatile Thiols (3-MH, 4-MMP, furfurylthiol) fruity: grapefruit, passion fruit, boxwood, toasty Found naturally in grapes as s-cysteine conjugates, released by yeast enzymes during fermentation

I hope that next time you encounter any of these aromas, you’ll know what to do and where they come from in the winemaking process. Hydrogen sulfide will blow off with aeration, mercaptans will bind to a copper penny, and volatile thiols may appear only after a few seconds in the mouth. There are many more known sulfur-derived compounds in wine, so get out there and smell the sulfur!

Further reading
Jamie Goode article on screwcaps and sulfur compounds
Descriptors of many aroma compounds: Flavornet
Great overview of sulfur in wine: Modulation of Sulfur Compounds by Wine Yeast
Perception of S-Cysteine Conjugates of Volatile Thiols

Tom Mansell

Tom Mansell is a PhD candidate in chemical engineering at Cornell University in Ithaca, NY. He is borderline obsessed with the science of wine and winemaking. His blog, Ithacork, focuses on Finger Lakes wines and always includes a “Science!” section, which gets down to technical details for the hardcore wine geek. He is also the Science Editor for The New York Cork Report. Follow him on Twitter @mrmansell.

About The Author

Tom Mansell
Science Editor

Tom Mansell is the Science Editor here at Palate Press and a member of the Editorial Board. He has a PhD in chemical engineering from Cornell University, where he also learned to love the wines of the Finger Lakes. He is also the Science Editor for The New York Cork Report. Tom is currently living in Boulder, CO, where he is a researcher at the University of Colorado. Follow him on Twitter @mrmansell.

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21 Responses

  1. Sondra Barrett

    What a great and useful article! Every kind of sulfur compound that help or damage wine. Thanks. I’ve always wanted that information in one place.

  2. Darby

    A great summary for those of us who forgot our high school chemistry. The question remains Why do some wine makers go overboard with the sulphur additives?

  3. Tom Mansell


    Thanks! There are lots more sulfur compounds out there than I could list here, but I tried to give a general overview.


    What’s overboard? Winemakers generally don’t just dump the stuff in to the legal limit (350 ppm in the US, well above the detection threshold).

    There’s a lot to consider when adding sulfites. First, the pH of a wine drastically affects the amount of molecular SO2 (the antimicrobial agent), and higher pH wines need lots of sulfites for effective antimicrobial activity(i.e., control against spoilage). Second, sulfites bind to acetaldehyde and reducing sugars, so if there is any of that around (i.e., in a sweet white), you’ll need more as well. This is why I have found that lots of German Rieslings with residual sugar (think Nahe, Mosel) have a whiff of SO2 on the nose. In general, sulfites are not harmful to 99% of the population (minus the minor nasal irritation/odor), so the potential for spoilage/oxidation during aging is great motivation for sulfite addition.

  4. Alec White

    I’ve been a student of wine since 1972 and one of the biggest challenges for me has been to pinpoint why a wine is off and the cause of the problem. While there is no simple cheat sheet that covers all the potential faults, Tom’s article is a great reference. Keep writing Tom, I look forward to reading more from you.

  5. Ward Kadel - @drXeNo

    Wow, this is just an outstanding breakdown of sulfur in wine. Thank you Tom! I knew a fair amount of this, but I still came out very far ahead in my understanding of this complex portion of winemaking. Cheers!

  6. Andrew Lazorchak

    This is a great article. I believe that white wines are usually dosed with more Sulfites than reds, hence the reason why decanting a white is helpful, is this a fair assumption?

    And I am piqued by Thiols, I will look up more on furfurylthiol, but are thiol compounds varietal specific or just a chemical action? For instance a Syrah can pick up a funky nose (which I like) at certain points of it’s bottle-aging, yet it can also re-integrate…Anyway – thanks for the killer article!!!

  7. Melinda

    Excellent article! I have enjoyed reading all your wine science education at your site too. Also, I read a book recently about closures (“To Cork or Not to Cork” by George M. Taber) which discussed the whole screw cap and redox issue along with everything you can imagine about closures. After reading that book, I became much more aware of the effects of different closures. One experience I had with a bottle of California Sauvignon Blanc recently, certainly brought what you wrote here and what I read, to life. It had a screw cap closure. I opened the bottle and was immediately accosted by Sulfur Dioxide (SO2) “burnt match/flint” and Hydrogen Sulfide (H2S) (rotten eggs). I thought that it would blow off after a while but it never did even after several days. I’ve had many other screw cap wines and never had this issue. The wine was wasted but it was a good sensory learning experience.

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  9. Peter LLOYD

    Thanks for a most interesting account, which I have so far only skimmed.

    I may have missed it in your account but did not see the other phenomenon I know about. My understanding (and direct experience as a sufferer) was that a percentage of us cannot easily digest sulphur compounds. This means that I can suffer from a “hangover” from drinking one glass of wine, but vodka etc is much better.

    I believe I also can have this problem from eating grapes etc which have been dusted or sprayed with sulphur.

    I read in a guide to preservatives that the toxins stay in the blood for a longer period with people whose livers cannot quickly dispose of them. (Genetic or from childhood exposure to eg sulphur drugs ?)

    Grateful any information and what can we sufferers do about it ? Do the anti-sulpher compound work ?